The Lusaka South Multi-Facility Economic Zone (LSMFEZ) was declared as a Multi-Facility Economic Zone (MFEZ) on 28 June 2010 under Statutory Instrument No. 47 of 2010 by the Government of the Republic of Zambia. 

The LSMFEZ is managed by Lusaka South Multi-Facility Economic Zone Limited, a company that was incorporated on 25 June 2012. The LSMFEZ has a total area of 2,100 hectares.

LSMFEZ is a public sector led development in which the Government is providing the requisite infrastructure and utility services such as roads, electricity, solid waste management and sewerage treatment facilities.

LSMFEZ is approximately 10 kilometers from the Lusaka City Center and 21 kilometers from Kenneth Kaunda International Airport. The zone is accessible through the Leopards Hill Road and Chifwema Road. An alternative road to the site is the Lusaka Inner Ring Road through Chilenje South residential area.